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Comprehensive real-time epidemiological data from respiratory infections in Finland between 2010 and 2014 obtained from an automated and multianalyte mariPOC (R) respiratory pathogen test

机译:通过自动和多分析物mariPOC(R)呼吸道病原体检测获得的2010年至2014年之间芬兰呼吸道感染的实时综合流行病学数据

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摘要

Respiratory viruses cause seasonal epidemics every year. Several respiratory pathogens are circulating simultaneously and typical symptoms of different respiratory infections are alike, meaning it is challenging to identify and diagnose different respiratory pathogens based on symptoms alone. mariPOC (R) is an automated, multianalyte antigen test which allows the rapid detection of nine respiratory infection pathogens [influenza A and B viruses, respiratory syncytial virus (RSV), human metapneumovirus, adenovirus, parainfluenza 1-3 viruses and pneumococci] from a single nasopharyngeal swab or aspirate samples, and, in addition, can be linked to laboratory information systems. During the study period from November 2010 to June 2014, a total of 22, 485 multianalyte respi tests were performed in the 14 participating laboratories in Finland and, in total, 6897 positive analyte results were recorded. Of the tested samples, 25 % were positive for one respiratory pathogen, with RSV (9.8 %) and influenza A virus (7.2 %) being the most common findings, and 0.65 % of the samples were multivirus-positive. Only small geographical variations in seasonal epidemics occurred. Our results show that the mariPOC (R) multianalyte respi test allows simultaneous detection of several respiratory pathogens in real time. The results are reliable and give the clinician a picture of the current epidemiological situation, thus minimising guesswork.
机译:呼吸道病毒每年导致季节性流行病。几种呼吸道病原体同时传播,不同呼吸道感染的典型症状相似,这意味着仅根据症状来识别和诊断不同的呼吸道病原体是一项挑战。 mariPOC(R)是一种自动化的多分析物抗原测试,可快速检测来自以下人群的9种呼吸道感染病原体[A和B型流感病毒,呼吸道合胞病毒(RSV),人间质肺病毒,腺病毒,1-3型副流感病毒和肺炎球菌]。单个鼻咽拭子或抽吸样品,此外,还可以链接到实验室信息系统。在2010年11月至2014年6月的研究期间,芬兰的14个参与实验室共进行了22项485种多分析物Respi测试,总共记录了6897份阳性分析物结果。在测试样本中,有25%的一种呼吸道病原体呈阳性,最常见的是RSV(9.8%)和甲型流感病毒(7.2%),而0.65%的样本是多病毒阳性的。季节性流行只发生了很小的地理变化。我们的结果表明,mariPOC(R)多分析物Respi测试可以实时同时检测几种呼吸道病原体。结果可靠,并为临床医生提供了当前流行病学情况的图片,从而最大程度地减少了猜测。

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